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Cussó, Olaf
Ribas Salamaña, Xavi Lloret Fillol, Julio Costas Salgueiro, Miquel |
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2015 | |
Highly enantioselective epoxidation of α-substituted styrenes with aqueous H2O2 is described by using a chiral iron complex as the catalyst and N-protected amino acids (AAs) as coligands. The amino acids synergistically cooperate with the iron center in promoting an efficient activation of H2O2 to catalyze epoxidation of this challenging class of substrates with good yields and stereoselectivities (up to 97 % ee) in short reaction times We acknowledge group LIPPSO from UdG for providing amino acid samples and A. Riera (IRB) for access to a polarimeter. We acknowledge financial support from the European Research Council (ERC-2009-StG-239910), MINECO of Spain (CTQ2012-37420-C02-01/BQU, CSD2010-00065), and Generalitat de Catalunya (2009SGR637). J.L.-F. thanks MICINN for a RyC contract. X.R. and M.C. thank ICREA-Academia awards |
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application/pdf | |
1433-7851 (versió paper) 1521-3773 (versió electrònica) |
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http://hdl.handle.net/10256/12060 | |
eng | |
Wiley-VCH Verlag | |
MINECO/PN 2013-2015/CTQ2012-37420-C02-01 MICINN/PN 2010-2016/CSD2010-00065 AGAUR/2009-2014/2009 SGR-637 Reproducció digital del document publicat a: http://dx.doi.org/10.1002/anie.201410557 Articles publicats (D-Q) info:eu-repo/grantAgreement/EC/FP7/239910 |
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© Angewandte Chemie-International Edition, 2015, vol. 54, núm. 9, p. 2729–2733 | |
Tots els drets reservats | |
Aminoà cids
Amino acids Catà lisi asimètrica Enantioselective catalysis |
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Synergistic Interplay of a Non-Heme Iron Catalyst and Amino Acid Coligands in H2O2 Activation for Asymmetric Epoxidation of α-Alkyl-Substituted Styrenes | |
info:eu-repo/semantics/article | |
DUGiDocs |