DUGi: Ítem | DUGiDocs - An integrin-targeted photoactivatable Pt(iv) complex as a selective anticancer pro-drug: Synthesis and photoactivation studies

Ítem

Autor:	Gandioso, Albert Shaili, Evyenia Massaguer i Vall-llovera, Anna Artigas, Gerard González-Cantó, Alejandro Woods, Julie A. Sadler, Evyenia Marchán, Vicente
Data:	2015
Resum:	A new anticancer agent based on the conjugation of a photoactivatable Pt(iv) pro-drug to a cyclic RGD-containing peptide is described. Upon visible light irradiation, phototoxicity was induced preferentially in SK-MEL-28 melanoma cancer cells overexpressing αVβ3 integrin compared to control DU-145 human prostate carcinoma cells
Format:	application/pdf
ISSN:	1359-7345 (versió paper) 1364-548X (versió electrònica)
Accés al document:	http://hdl.handle.net/10256/12279
Llenguatge:	eng
Editor:	Royal Society of Chemistry (RSC)
Col·lecció:	Reproducció digital del document publicat a: http://dx.doi.org/10.1039/C5CC03180J Articles publicats (D-B)
És part de:	© Chemical Communications, 2015, vol. 51, p. 9169-9172
Drets:	Attribution 3.0 Spain
URI Drets:	http://creativecommons.org/licenses/by/3.0/es/
Matèria:	Medicaments antineoplàstics Antineoplastic agents
Títol:	An integrin-targeted photoactivatable Pt(iv) complex as a selective anticancer pro-drug: Synthesis and photoactivation studies
Tipus:	info:eu-repo/semantics/article
Repositori:	DUGiDocs