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The dietary intake of wheat and other cereal grains and their role in inflammation

Wheat is one of the most consumed cereal grains worldwide and makes up a substantial part of the human diet. Although government-supported dietary guidelines in Europe and the U.S.A advise individuals to eat adequate amounts of (whole) grain products per day, cereal grains contain "anti-nutrients," such as wheat gluten and wheat lectin, that in humans can elicit dysfunction and disease. In this review we discuss evidence from in vitro, in vivo and human intervention studies that describe how the consumption of wheat, but also other cereal grains, can contribute to the manifestation of chronic inflammation and autoimmune diseases by increasing intestinal permeability and initiating a pro-inflammatory immune response

MDPI (Multidisciplinary Digital Publishing Institute)

Author: De Punder, Karin
Pruimboom, Leo
Date: 2013 March 12
Abstract: Wheat is one of the most consumed cereal grains worldwide and makes up a substantial part of the human diet. Although government-supported dietary guidelines in Europe and the U.S.A advise individuals to eat adequate amounts of (whole) grain products per day, cereal grains contain "anti-nutrients," such as wheat gluten and wheat lectin, that in humans can elicit dysfunction and disease. In this review we discuss evidence from in vitro, in vivo and human intervention studies that describe how the consumption of wheat, but also other cereal grains, can contribute to the manifestation of chronic inflammation and autoimmune diseases by increasing intestinal permeability and initiating a pro-inflammatory immune response
Format: application/pdf
Document access: http://hdl.handle.net/10256/12964
Language: eng
Publisher: MDPI (Multidisciplinary Digital Publishing Institute)
Collection: info:eu-repo/semantics/altIdentifier/doi/10.3390/nu5030771
info:eu-repo/semantics/altIdentifier/eissn/2072-6643
Rights: Attribution 3.0 Spain
Rights URI: http://creativecommons.org/licenses/by/3.0/es/
Subject: Malaltia celíaca
Celiac disease
Dieta sense gluten
Gluten-free diet
Aparell digestiu -- Malalties
Digestive organs -- Diseases
Title: The dietary intake of wheat and other cereal grains and their role in inflammation
Type: info:eu-repo/semantics/article
Repository: DUGiDocs

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