Item


Modeling the Error of the Medtronic Paradigm Veo Enlite Glucose Sensor

Continuous glucose monitors (CGMs) are prone to inaccuracy due to time lags, sensor drift, calibration errors, and measurement noise. The aim of this study is to derive the model of the error of the second generation Medtronic Paradigm Veo Enlite (ENL) sensor and compare it with the Dexcom SEVEN PLUS (7P), G4 PLATINUM (G4P), and advanced G4 for Artificial Pancreas studies (G4AP) systems. An enhanced methodology to a previously employed technique was utilized to dissect the sensor error into several components. The dataset used included 37 inpatient sessions in 10 subjects with type 1 diabetes (T1D), in which CGMs were worn in parallel and blood glucose (BG) samples were analyzed every 15 ± 5 min Calibration error and sensor drift of the ENL sensor was best described by a linear relationship related to the gain and offset. The mean time lag estimated by the model is 9.4 ± 6.5 min. The overall average mean absolute relative difference (MARD) of the ENL sensor was 11.68 ± 5.07% Calibration error had the highest contribution to total error in the ENL sensor. This was also reported in the 7P, G4P, and G4AP. The model of the ENL sensor error will be useful to test the in silico performance of CGM-based applications, i.e., the artificial pancreas, employing this kind of sensor

This project has been partially supported by the Spanish Government through Grants DPI-2013-46982-C2-2-R and DPI-2016-78831-C2-2-R, the National Council of Technological and Scientific Development, CNPq Brazil through Grant 202050/2015-7, the University of Girona through Grant BR2014/51, and the Agency for Management of University and Research Grants of the Government of Catalonia, Spain (Beatriu de Pinós [BP-DGR 2013])

Sensors, 2017, vol. 17, núm. 6, p. 1361

MDPI (Multidisciplinary Digital Publishing Institute)

Manager: Ministerio de Economía y Competitividad (Espanya)
Author: Biagi, Lyvia
Ramkissoon, Charrise M.
Facchinetti, Andrea
Leal Moncada, Yenny Teresa
Vehí, Josep
Date: 2017 June 12
Abstract: Continuous glucose monitors (CGMs) are prone to inaccuracy due to time lags, sensor drift, calibration errors, and measurement noise. The aim of this study is to derive the model of the error of the second generation Medtronic Paradigm Veo Enlite (ENL) sensor and compare it with the Dexcom SEVEN PLUS (7P), G4 PLATINUM (G4P), and advanced G4 for Artificial Pancreas studies (G4AP) systems. An enhanced methodology to a previously employed technique was utilized to dissect the sensor error into several components. The dataset used included 37 inpatient sessions in 10 subjects with type 1 diabetes (T1D), in which CGMs were worn in parallel and blood glucose (BG) samples were analyzed every 15 ± 5 min Calibration error and sensor drift of the ENL sensor was best described by a linear relationship related to the gain and offset. The mean time lag estimated by the model is 9.4 ± 6.5 min. The overall average mean absolute relative difference (MARD) of the ENL sensor was 11.68 ± 5.07% Calibration error had the highest contribution to total error in the ENL sensor. This was also reported in the 7P, G4P, and G4AP. The model of the ENL sensor error will be useful to test the in silico performance of CGM-based applications, i.e., the artificial pancreas, employing this kind of sensor
This project has been partially supported by the Spanish Government through Grants DPI-2013-46982-C2-2-R and DPI-2016-78831-C2-2-R, the National Council of Technological and Scientific Development, CNPq Brazil through Grant 202050/2015-7, the University of Girona through Grant BR2014/51, and the Agency for Management of University and Research Grants of the Government of Catalonia, Spain (Beatriu de Pinós [BP-DGR 2013])
Format: application/pdf
Citation: 027175
ISSN: 1424-8220
Document access: http://hdl.handle.net/10256/14267
Language: eng
Publisher: MDPI (Multidisciplinary Digital Publishing Institute)
Collection: MINECO/PE 2014-2017/DPI2013‐46982‐C2‐2‐R
MINECO/PE 2016-2019/DPI2016-78831-C2-2-R
Reproducció digital del document publicat a: http://dx.doi.org/10.3390/s17061361
Articles publicats (D-IMA)
Is part of: Sensors, 2017, vol. 17, núm. 6, p. 1361
Rights: Attribution 3.0 Spain
Rights URI: http://creativecommons.org/licenses/by/3.0/es/
Subject: Biosensors
Medicina -- Aparells i instruments
Medical instruments and apparatus
Biosensors -- Calibratge
Biosensors -- Calibration
Diabetis
Diabetes
Title: Modeling the Error of the Medtronic Paradigm Veo Enlite Glucose Sensor
Type: info:eu-repo/semantics/article
Repository: DUGiDocs

Subjects

Authors