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Silva Blas, Yolanda | |
Universitat de Girona. Facultat de Medicina | |
Encina GarcÃa, Paula | |
2022 November | |
Background: RACECAT was the first randomized study, in our territory, designed to
evaluate if in nonurban areas with limited access to thrombectomy-capable centers,
patients with large vessel occlusion would benefit from going directly to a center with
the capacity to perform a mechanical thrombectomy compared with transport them to
the closest local stroke center. 1401 patients were randomized into two groups: one
group followed the usual route to the nearest stroke center (drip-and-ship model) and
the other group was sent directly to a thrombectomy-capable center (mothership
model). The scale used to recognize patients with LVO (RACE scale >4) did not allow
differentiation between ischemic and hemorrhagic strokes, and therefore, 314 patients
with intracerebral hemorrhage were included in the study. This meant that
approximately half of these patients were referred to a more distant center with an
average delay in hospital care of 49 minutes more than the group that went to the
nearest stroke center. Intracerebral hemorrhage is a devastating type of stroke and
during the first 3 hours, neurological deterioration can occur, mostly due to hematoma
expansion. Early and intensive blood pressure control has proven to be effective in
tapering hematoma expansion, especially during the first hours.
Objective: The aim of this study is whether bypassing the nearest local stroke center is
harmful to patients suffering an intracerebral hemorrhage. Our main objective is to
compare the Rankin score at 90 days of patients with intracerebral hemorrhage
according to the prehospital circuit (drip-and-ship vs. mothership) they had in the
RACECAT study.
Design: This study will be a retrospective subanalysis of RACECAT prospective cohorts.
It is a multicenter study that includes 28 centers in Catalonia.
Participants: Patients older than 18 years old with intracerebral hemorrhage previously
included in the RACECAT study.
Methods: All the data needed is going to be collected from the CICAT database. For the
statistical analysis, we will use χ2-test and Exact Fisher test for qualitative variables,
Mann-Whitney for discrete quantitative variables, and T-student to compare qualitative
with quantitative variables. A confidence interval of 95% will be assumed and a p<0,05
will be considered statistically significant. The association between the independent and
the dependent variables will be adjusted by a logic regression and general linear models
in order to avoid possible confounders or effect modifiers 3 |
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application/pdf | |
http://hdl.handle.net/10256/22971 | |
eng | |
Attribution-NonCommercial-NoDerivatives 4.0 International | |
http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
Hemorrà gia cerebral
Brain -- Hemorrhage Urgències mèdiques Medical emergencies Hospitals -- Serveis d’urgències Hospitals -- Emergency services |
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Effect of prehospital transfer model in patients with intracerebral hemorrhage: a RACECAT sub-analysis | |
info:eu-repo/semantics/bachelorThesis | |
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