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Determination of a broad spectrum of pharmaceuticals and endocrine disruptors in biofilm from a waste water treatment plant-impacted river

Wastewater treatment plants (WWTPs) are one of the main sources of pharmaceuticals and endocrine disrupting compounds in freshwater ecosystems, and several studies have reported bioaccumulation of these compounds in different organisms in those ecosystems. River biofilms are exceptional indicators of pollution, but very few studies have focused on the accumulation of these emerging contaminants. The objectives of this study were first to develop an efficient analytical methodology for the simultaneous analysis of 44 pharmaceuticals and 13 endocrine disrupting compounds in biofilm, and second, to assess persistence, distribution, and bioaccumulation of these contaminants in natural biofilms inhabiting a WWTP-impacted river. The method is based on pressurized liquid extraction, purification by solid-phase extraction, and analysis by ultra performance liquid chromatography coupled to a mass spectrometer (UPLC-MS/MS) in tandem. Recoveries for pharmaceuticals were 31-137%, and for endocrine disruptors 32-93%. Method detection limits for endocrine disruptors were in the range of 0.2-2.4ng g-1, and for pharmaceuticals, 0.07-6.7ng g-1. A total of five endocrine disruptors and seven pharmaceuticals were detected in field samples at concentrations up to 100ng g-1

This study has been co-financed by the Spanish Ministry of Economy and Competitiveness through the project WATER-Fate (CTM2012-38314-C0201), by the EU through the FP7 project GLOBAQUA (Grant agreement No. 603629) and by the European Union through the European Regional Development Fund (ERDF). This work was partly supported by the Economy and Knowledge Department of the Catalan Government (Consolidated Research Group 2014 SGR 291 - ICRA)

Elsevier

Author: Huerta Buitrago, Belinda
Rodríguez Mozaz, Sara
Nannou, Christina
Nakis, L.
Ruhí i Vidal, Albert
Acuña i Salazar, Vicenç
Sabater, Sergi
Barceló i Cullerés, Damià
Abstract: Wastewater treatment plants (WWTPs) are one of the main sources of pharmaceuticals and endocrine disrupting compounds in freshwater ecosystems, and several studies have reported bioaccumulation of these compounds in different organisms in those ecosystems. River biofilms are exceptional indicators of pollution, but very few studies have focused on the accumulation of these emerging contaminants. The objectives of this study were first to develop an efficient analytical methodology for the simultaneous analysis of 44 pharmaceuticals and 13 endocrine disrupting compounds in biofilm, and second, to assess persistence, distribution, and bioaccumulation of these contaminants in natural biofilms inhabiting a WWTP-impacted river. The method is based on pressurized liquid extraction, purification by solid-phase extraction, and analysis by ultra performance liquid chromatography coupled to a mass spectrometer (UPLC-MS/MS) in tandem. Recoveries for pharmaceuticals were 31-137%, and for endocrine disruptors 32-93%. Method detection limits for endocrine disruptors were in the range of 0.2-2.4ng g-1, and for pharmaceuticals, 0.07-6.7ng g-1. A total of five endocrine disruptors and seven pharmaceuticals were detected in field samples at concentrations up to 100ng g-1
This study has been co-financed by the Spanish Ministry of Economy and Competitiveness through the project WATER-Fate (CTM2012-38314-C0201), by the EU through the FP7 project GLOBAQUA (Grant agreement No. 603629) and by the European Union through the European Regional Development Fund (ERDF). This work was partly supported by the Economy and Knowledge Department of the Catalan Government (Consolidated Research Group 2014 SGR 291 - ICRA)
Document access: http://hdl.handle.net/2072/266424
Language: eng
Publisher: Elsevier
Rights: Reconeixement-NoComercial-SenseObraDerivada 3.0 Espanya
Rights URI: http://creativecommons.org/licenses/by-nc-nd/3.0/es/deed.ca
Subject: Aigua -- Contaminació
Water -- Pollution
Disruptors endocrins
Endocrine disrupting chemicals
Contaminants emergents en l’aigua
Emerging contaminants in water
Biofilms
Title: Determination of a broad spectrum of pharmaceuticals and endocrine disruptors in biofilm from a waste water treatment plant-impacted river
Type: info:eu-repo/semantics/article
Repository: Recercat

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