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A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

An efficient method for the synthesis of N-arylated pyridazinones from potassium 2-furantrifluoroborate and aryldiazonium salts is described. The reaction was run in water at 0-5 °C in short reaction times and without any catalyst or additive. A mechanistic proposal is made based on the experimental data and DFT calculations

We thank MINECO (Projects CTQ2011-23121, 23156, and CTQ2012-32436) and the Generalitat de Catalunya (Project 2009SGR637, ICREA Academia for M.S.) for financial support

Elsevier

Director: Ministerio de Ciencia e Innovación (Espanya)
Generalitat de Catalunya. Agència de Gestió d’Ajuts Universitaris i de Recerca
Autor: El Bakouri, Ouissam
Cassú Ponsatí, Daniel
Solà i Puig, Miquel
Parella Coll, Teodor
Pla i Quintana, Anna
Roglans i Ribas, Anna
Resum: An efficient method for the synthesis of N-arylated pyridazinones from potassium 2-furantrifluoroborate and aryldiazonium salts is described. The reaction was run in water at 0-5 °C in short reaction times and without any catalyst or additive. A mechanistic proposal is made based on the experimental data and DFT calculations
We thank MINECO (Projects CTQ2011-23121, 23156, and CTQ2012-32436) and the Generalitat de Catalunya (Project 2009SGR637, ICREA Academia for M.S.) for financial support
Accés al document: http://hdl.handle.net/2072/296583
Llenguatge: eng
Editor: Elsevier
Drets: Tots els drets reservats
Matèria: Funcional de densitat, Teoria del
Density functionals
Compost de diazoni
Diazonium compounds
Títol: A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts
Tipus: info:eu-repo/semantics/article
Repositori: Recercat

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