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Selective C–H oxidation catalyzed by metalloporphyrins

Selective oxidation of saturated C–H bonds remains a challenge in modern chemistry. The inert nature of such bonds requires the use of highly reactive reagents, and this poses major challenges in terms of chemo, regio and stereoselectivity. Metalloporphyrins based in iron, manganese and ruthenium constitute a unique family of catalysts capable of generating these highly reactive, but at the same time highly selective oxidants, thus exquisitely mediating selective oxidations of C–H bonds. The mechanisms underlying these reactions are collected and discussed in the present work. Recent advances in the application of these catalysts in the oxidation of complex organic molecules are also reviewed

Financial support for this work was provided by MEC-Spain (Project CTQ2009-08464), Generalitat de Catalunya (2009SGR637), and European Research Council for project ERC-2009-StG-239910. M.C. acknowledges an ICREA-Academia Award. Anna Company, Laura Gomez and Dr Julio Lloret are acknowledged by a critical reading of the manuscript

Manager: Ministerio de Ciencia e Innovación (Espanya)
Generalitat de Catalunya. Agència de Gestió d’Ajuts Universitaris i de Recerca
Author: Costas Salgueiro, Miquel
Abstract: Selective oxidation of saturated C–H bonds remains a challenge in modern chemistry. The inert nature of such bonds requires the use of highly reactive reagents, and this poses major challenges in terms of chemo, regio and stereoselectivity. Metalloporphyrins based in iron, manganese and ruthenium constitute a unique family of catalysts capable of generating these highly reactive, but at the same time highly selective oxidants, thus exquisitely mediating selective oxidations of C–H bonds. The mechanisms underlying these reactions are collected and discussed in the present work. Recent advances in the application of these catalysts in the oxidation of complex organic molecules are also reviewed
Financial support for this work was provided by MEC-Spain (Project CTQ2009-08464), Generalitat de Catalunya (2009SGR637), and European Research Council for project ERC-2009-StG-239910. M.C. acknowledges an ICREA-Academia Award. Anna Company, Laura Gomez and Dr Julio Lloret are acknowledged by a critical reading of the manuscript
Document access: http://hdl.handle.net/2072/300381
Language: eng
Rights: Tots els drets reservats
Subject: Reaccions químiques
Chemical reactions
Oxidació
Oxidation
Catalitzadors metàl·lics
Metal catalysts
Title: Selective C–H oxidation catalyzed by metalloporphyrins
Type: info:eu-repo/semantics/article
Repository: Recercat

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