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Evidence that steric factors modulate reactivity of tautomeric iron-oxo species in stereospecific alkane C-H hydroxylation

A new iron complex mediates stereospecific hydroxylation of alkyl C-H bonds with hydrogen peroxide, exhibiting excellent efficiency. Isotope labelling studies provide evidence that the relative reactivity of tautomerically related oxo-iron species responsible for the C-H hydroxylation reaction is dominated by steric factors

This work has been supported by the European Union (the Erasmus Mundus program), the International Research Training Group Metal Sites in Biomolecules: Structures, Regulation and Mechanisms (www.biometals.eu), and COST Action CM1003. M.C. acknowledges ERC-29910, MINECO of Spain for CTQ2012- 37420-C02-01/BQU and CSD2010-00065, catalan DIUE (2009SGR637) and an ICREA academia award. J.Ll. thanks MICINN for a RyC contract

漏 Chemical Communications, 2014, vol. 50, n煤m. 12, p. 1408-1410

Royal Society of Chemistry (RSC)

Author: Mitra, Mainak
Lloret Fillol, Julio
Haukka, Matti
Costas Salgueiro, Miquel
Nordlander, Ebbe
Date: 2014
Abstract: A new iron complex mediates stereospecific hydroxylation of alkyl C-H bonds with hydrogen peroxide, exhibiting excellent efficiency. Isotope labelling studies provide evidence that the relative reactivity of tautomerically related oxo-iron species responsible for the C-H hydroxylation reaction is dominated by steric factors
This work has been supported by the European Union (the Erasmus Mundus program), the International Research Training Group Metal Sites in Biomolecules: Structures, Regulation and Mechanisms (www.biometals.eu), and COST Action CM1003. M.C. acknowledges ERC-29910, MINECO of Spain for CTQ2012- 37420-C02-01/BQU and CSD2010-00065, catalan DIUE (2009SGR637) and an ICREA academia award. J.Ll. thanks MICINN for a RyC contract
Format: application/pdf
ISSN: 1359-7345 (versi贸 paper)
1364-548X (versi贸 electr貌nica)
Document access: http://hdl.handle.net/10256/12102
Language: eng
Publisher: Royal Society of Chemistry (RSC)
Collection: MINECO/PN 2013-2015/CTQ2012-37420-C02-01
MICINN/PN 2010-2016/CSD2010-00065
AGAUR/2009-2014/2009 SGR-637
Reproducci贸 digital del document publicat a: http://dx.doi.org/10.1039/c3cc47830k
Articles publicats (D-Q)
Is part of: 漏 Chemical Communications, 2014, vol. 50, n煤m. 12, p. 1408-1410
Rights: Attribution-NonCommercial 3.0 Spain
Rights URI: http://creativecommons.org/licenses/by-nc/3.0/es/
Subject: Oxidaci贸
Oxidation
Ferro -- Compostos
Iron compounds
Cat脿lisi
Catalysis
Title: Evidence that steric factors modulate reactivity of tautomeric iron-oxo species in stereospecific alkane C-H hydroxylation
Type: info:eu-repo/semantics/article
Repository: DUGiDocs

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