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Combined Analysis of the Short-Term Effects of Photochemical Air Pollutants on Mortality within the EMECAM Project

In recent years, some epidemiologic studies have attributed adverse effects of air pollutants on health not only to particles and sulfur dioxide but also to photochemical air pollutants (nitrogen dioxide and ozone). The effects are usually small, leading to some inconsistencies in the results of the studies. Furthermore, the different methodologic approaches of the studies used has made it difficult to derive generic conclusions. We provide here a quantitative summary of the short-term effects of photochemical air pollutants on mortality in seven Spanish cities involved in the EMECAM project, using generalized additive models from analyses of single and multiple pollutants. Nitrogen dioxide and ozone data were provided by seven EMECAM cities (Barcelona, Gijón, Huelva, Madrid, Oviedo, Seville, and Valencia). Mortality indicators included daily total mortality from all causes excluding external causes, daily cardiovascular mortality, and daily respiratory mortality. Individual estimates, obtained from city-specific generalized additive Poisson autoregressive models, were combined by means of fixed effects models and, if significant heterogeneity among local estimates was found, also by random effects models. Significant positive associations were found between daily mortality (all causes and cardiovascular) and NO2, once the rest of air pollutants were taken into account. A 10 μg/m3 increase in the 24-hr average 1-day NO2 level was associated with an increase in the daily number of deaths of 0.43% [95% confidence interval(CI), –0.003–0.86%] for all causes excluding external. In the case of significant relationships, relative risks for cause-specific mortality were nearly twice as much as that for total mortality for all the photochemical pollutants. Ozone was independently related only to cardiovascular daily mortality. No independent statistically significant relationship between photochemical air pollutants and respiratory mortality was found. The results in this study suggest that, given the present levels of photochemical pollutants, people living in Spanish cities are exposed to health risks derived from air pollution

© Environmental Health Perspectives, 2002, vol. 110, núm.3, p. 221-228

National Institute of Environmental Health Sciences

Author: Sáez Zafra, Marc
Ballester, Ferran
Barceló Rado, María Antonia
Pérez Hoyos, Santiago
Bellido, Juan
Tenías, José María
Ocaña, Ricardo
Figueiras, Adolfo
Arribas, Federico
Aragonés, Nuria
Tobías, Aurelio
Cirera, Lluís
Cañada, Álvaro
Date: 2002
Abstract: In recent years, some epidemiologic studies have attributed adverse effects of air pollutants on health not only to particles and sulfur dioxide but also to photochemical air pollutants (nitrogen dioxide and ozone). The effects are usually small, leading to some inconsistencies in the results of the studies. Furthermore, the different methodologic approaches of the studies used has made it difficult to derive generic conclusions. We provide here a quantitative summary of the short-term effects of photochemical air pollutants on mortality in seven Spanish cities involved in the EMECAM project, using generalized additive models from analyses of single and multiple pollutants. Nitrogen dioxide and ozone data were provided by seven EMECAM cities (Barcelona, Gijón, Huelva, Madrid, Oviedo, Seville, and Valencia). Mortality indicators included daily total mortality from all causes excluding external causes, daily cardiovascular mortality, and daily respiratory mortality. Individual estimates, obtained from city-specific generalized additive Poisson autoregressive models, were combined by means of fixed effects models and, if significant heterogeneity among local estimates was found, also by random effects models. Significant positive associations were found between daily mortality (all causes and cardiovascular) and NO2, once the rest of air pollutants were taken into account. A 10 μg/m3 increase in the 24-hr average 1-day NO2 level was associated with an increase in the daily number of deaths of 0.43% [95% confidence interval(CI), –0.003–0.86%] for all causes excluding external. In the case of significant relationships, relative risks for cause-specific mortality were nearly twice as much as that for total mortality for all the photochemical pollutants. Ozone was independently related only to cardiovascular daily mortality. No independent statistically significant relationship between photochemical air pollutants and respiratory mortality was found. The results in this study suggest that, given the present levels of photochemical pollutants, people living in Spanish cities are exposed to health risks derived from air pollution
Format: application/pdf
Citation: Saez, M., Ballester, F., Barceló, M.A., Pérez-Hoyos, S., Bellido, J., Tenías, J.M. et al. (2002). A Combined Analysis of the Short-Term Effects of Photochemical Air Pollutants on Mortality within the EMECAM Project. Environmental Health Perspectives, 110 (3), 221-228. Recuperat 12 setembre de 2011, a http://dx.doi.org/10.1289/ehp.02110221
ISSN: 0091-6765
Document access: http://hdl.handle.net/10256/3539
Language: eng
Publisher: National Institute of Environmental Health Sciences
Collection: Reproducció digital del document publicat a: http://dx.doi.org/10.1289/ehp.02110221
Articles publicats (D-EC)
Is part of: © Environmental Health Perspectives, 2002, vol. 110, núm.3, p. 221-228
Rights: Reproduced with permission from Environmental Health Perspectives
Subject: Aire -- Contaminació
Anàlisi combinatòria
Contaminants
Mortalitat
Air -- Pollution
Combinatorial analysis
Mortality
Pollutants
Title: Combined Analysis of the Short-Term Effects of Photochemical Air Pollutants on Mortality within the EMECAM Project
Type: info:eu-repo/semantics/article
Repository: DUGiDocs

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